We provide the CPA and AF data for the Affymetrix Human Mapping 100K and 500K Sets.
Bulks of the CPA data download are available.
Three query modes for the CPA data search are provided.
Three query modes for the AF data search are provided.
Bulks of the AF data download are available.
Welcome to send us your comment/suggestion.

Update: 02.25.2010>
Introduction
     We create the database of coefficient of preferential amplification/hybridization (CPA) and database of allele frequency (AF) for various ethnic populations (the African, Asian and Caucasian populations), SNP arrays (the Affymetrix GeneChip Human Mapping 100K and 500K Sets), and annotation versions (Years 2007 and 2008) for studies of pooled DNA analysis, population genetics, association mapping and chromosome aberration detection. The CPA/AF data queries and bulk data download are available.

Copyright claim

We welcome any noncommercial use of our database for your own research, but please don't redistribute the data in any form without the permission of authors. For free resource, we assume no warranty and no responsibility for the results of analyses.

Citation

Hsin-Chou Yang*, Hsin-Chi Lin, Mei-Chu Huang, Ling-Hui Li, Wen-Harn Pan, Jer-Yuarn Wu and Yuan-Tsong Chen (2010). A new analysis tool for individual-level allele frequency for genomic studies. BMC Genomics 11, 415.

Other References

1. Yang et al. (2005). New adjustment factors and sample size calculation in a DNA-pooling experiment with preferential amplification. Genetics 169: 399-410 (Pdf file is available at http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1448875&blobtype=pdf). 

2. Yang et al. (2006). PDA: pooled DNA analyzer. BMC Bioinformatics, 7: 233. (Pdf file is available at http://www.biomedcentral.com/1471-2105/7/233, and PDA software is available at http://www.csjfann.ibms.sinica.edu.tw/EAG/Program/PDA/Pda.php).

3. Yang et al. (2006). A genome-wide study of preferential amplification/hybridization in microarray-based pooled DNA experiments. Nucleic Acids Research 34, e106. (Pdf file is available at http://nar.oxfordjournals.org/cgi/reprint/34/15/e106)

4. Yang et al. (2008). MPDA: microarray-based pooled DNA analyzer. BMC Bioinformatics 9, 196. (http://www.biomedcentral.com/content/pdf/1471-2105-9-196.pdf), and MPDA software is available at http://www.stat.sinica.edu.tw/hsinchou/genetics/pooledDNA/mpda.htm).